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Since our founding in 2010, MS Biotec has pioneered the use of the rumen-native bacteria Mega e® to enable regulation of rumen pH and to stimulate a healthy rumen environment.

MS Biotec and its affiliates are the world’s only commercial providers of Mega e, and the company is a co-owner of the patent for a superior strain of this prolific lactic acid-utilizing bacteria (Megasphaera elsdenii NCIMB 41125).

Our signature line of Lactipro® products harness the power of Mega e to enable beef and dairy producers to support healthy rumen pH and improve profitability. We invented anaerobic processes and packaging to ensure each Lactipro application maintains maximum potency from production to delivery. Our state-of-the-art labs and production lines are the only facilities in the world that can produce viable Mega e for cattle on a commercial scale.

Celebrating 10 years logo

Celebrating a Decade of Mega e Innovation

In 2020, we celebrate our 10th year in business with the launch of LactiproFLX® and the Fall 2020 release of LactiproNXT®. After a rigorous development process, we are proud to announce a Lactipro capsule and drench containing a high concentration of Mega e with stability for months instead of days.

Celebrate Video

10 years of Lactipro

Learn more about the history of MS Biotec and see our two new innovations in use.

Learn more about Lactipro
  1. 1993

    A team in South Africa isolates the superior strain of Megasphaera elsdenii NCIMB 41125.

  2. 1996

    The team shelves the work due to lack of success with freeze drying and product development.

  3. 2003

    Leander van der Walt joins South African team addressing bovine acidosis and obtains South African patent for Mega e strain NCIMB 41125 and its uses, and for proliferation and delivery devices. Van der Walt begins work with Kansas State University to conduct foundational animal and microbiology work.

  4. 2009

    U.S. patent for Megasphaera elsdenii NCIMB 41125 is granted. MS Biotec is established in the U.S. Work begins on innovative anaerobic development in a specially designed facility close to Kansas State University.

  5. 2010

    FDA approval is received for Lactipro. Anaerobic development and production facility opened in Wamego, Kansas, in the vicinity of leading scientists at Kansas State University. First generation of Lactipro introduced in U.S. and first commercial dose administered.

  6. 2014

    Expansion of production facility to second building in Wamego, Kansas

  7. 2015

    2nd generation product, Lactipro advance®, introduced to the market

  8. 2016

    Expansion of second building to accommodate more advanced quality control and R&D

  9. 2017

    Provisional patent for freeze drying filed

  10. 2018

    Investment from Paine Schwartz Partners accelerates company’s growth. Patent application for freeze drying and for use in poultry, equine, and silage.

  11. 2020

    LactiproFLX and LactiproNXT introduced as 3rd generation innovations

A History of Innovation

The history of MS Biotec is a story of innovation and persistence — from early research into rumen health, to founding the company in 2010 to bring Mega e to scale, to breakthroughs in freeze-drying that enabled the 2020 launch of LactiproFLX and LactiproNXT.

Our founder and CEO Leander van der Walt first learned of Megasphaera elsdenii in his home country of South Africa in 2003. Recognizing the potential of the rumen-native bacteria to support animal health and diet transitions, the South African team patented the most effective strain of Mega e evaluated (Megasphaera elsdenii NCIMB 41125). A U.S. patent, FDA use approval and advances in anaerobic processes and packaging followed, culminating in the founding of MS Biotec and the first commercial application at a U.S. feedyard in 2010.

Since then, MS Biotec has continued to pioneer the science — evolving Lactipro products, expanding its team, and innovating anaerobic processes and packaging at its state-of-the-art R&D and production facility in Wamego, Kansas.

MS Biotec Leadership Team

Leander van der Walt main image Leander van der Walt Chief Executive Officer Read Bio Carl Guthrie main image Carl A. Guthrie, D.V.M. Chief Commercial Officer Read Bio Celine Aperce main image Celine Aperce, Ph.D. Director of R&D and Quality Assurance Read Bio Justin Harpe main image Justin Harpe Director of Production Operations Read Bio
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Leander van der Walt picture

Leander van der Walt

Chief Executive Officer

Leander serves as CEO of MS Biotec and guides the organization’s strategic focus and vision.

Leander has more than 18 years of experience commercializing Megasphaera elsdenii for the cattle market, starting in South Africa. He moved his family to the U.S. in 2010 and became MS Biotec’s first employee at the company’s founding. Since, Leander has grown the business and assumed various management roles to ensure strategic growth and development.

Leander holds a Master’s in Business Leadership from the University of South Africa and an Animal Science degree from the University of Orange Free State.


Carl A. Guthrie picture

Carl Guthrie D.V.M.

Chief Commercial Officer

Carl is the Chief Commercial Officer and provides leadership for all sales, marketing and technical teams.

Carl joined MS Biotec in 2018 after a productive, 22-year career with Elanco where he served as Regional Sales Director for Cattle and Swine and Director of Technical Consulting for the Beef Business Unit. Prior to joining Elanco, Carl owned and operated a private veterinary practice in Nebraska for several years.

Carl earned his doctorate in veterinary medicine and bachelor’s degree in biochemistry from Oklahoma State University. Carl is married with one daughter in high school.


Celine Aperce picture

Celine Aperce, Ph.D.

Director of R&D and Quality Assurance

As MS Biotec’s Director of Research and Development as well as Quality Assurance, Celine directs a large team of researchers focused on new innovations and oversees all aspects of product quality.

Celine has worked with anaerobic bacteria and Megasphaera for 10 years. She came to Kansas State University in 2007 for a semester abroad for her “Ingenieur degree” at the Engineering School of Purpan (Master Equivalent). That year, she began her graduate work at K-State focusing on monogastric physiology. In 2009, she began her Ph.D. studies in ruminant nutrition, focusing on factors affecting Escherichia coli O157 colonization of the gastrointestinal tract of feedlot cattle. She acquired extensive experience working in vitro and in vivo with Megasphaera elsdenii in equine, poultry and ruminants.

Celine joined MS Biotec in 2013 and has grown the department to 20 personnel focused on research, development, and quality. She is from Toulouse, France and has an Ingenieur degree from the Engineering School of Purpan and a Masters and Ph.D. degree in Animal Science from Kansas State University.


Justin Harpe picture

Justin Harpe

Director of Operations

Justin is the Director of Production Operations and oversees a world-class facility specialized in the production of anaerobic bacteria.

Justin is a Licensed Electrician who joined MS Biotec as an Equipment Specialist in 2011. He was instrumental in the design and build of MS Biotec’s primary production line in 2012. Since, Justin has expanded the production facility and office space and developed the production process to freeze-dry anaerobic bacteria for use in a new generation of MS Biotec products.

Justin was born in Traverse City, Michigan and moved to Saint Marys, Kansas as a child. He attended Saint Mary’s Academy and later apprenticed with the electrical industry through the IBEW. He went on to pursue a successful electrical career in both commercial and industrial settings for 14 years before joining MS Biotec. While attending Saint Mary’s Academy, Justin met and later married his high school sweetheart and they enjoy raising their 14 children in the Saint Mary’s area.



MS Biotec’s Research, Development and Production Facility in Wamego, Kansas

Our state-of-the-art operation in Wamego, Kansas, is one of three MS Biotec facilities in the world that can produce viable Mega e on a commercial scale. Our PhD-led teams have pioneered the use of Mega e, from early drench applications to today’s LactiproFLX and LactiproNXT. Our proximity to leading scientists, livestock producers, nutritionists and veterinarians along the Midwest’s animal health research corridor has led to important breakthroughs and collaborations.